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Fadrozole hydrochloride

Fadrozole hydrochloride

€49.00

Excl. VAT

Item no.	HY-14247-5mg
Manufacturer	MedChem Express
CASRN	102676-31-3
Amount	5 mg
Category	Food Safety Hormones Metabolism Diabetes Glucose Homeostasis Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.22
Formula	C14H14ClN3
Citations	[1]Browne LJ, et al. Fadrozole hydrochloride: a potent, selective, nonsteroidal inhibitor of aromatase for the treatment of estrogen-dependent disease. J Med Chem. 1991 Feb;34(2):725-36. [2]Gunson DE, et al. Prevention of spontaneous tumours in female rats by fadrozole hydrochloride, an aromatase inhibitor. Br J Cancer. 1995 Jul;72(1):72-5. [3]Morales-Montor J, et al. Inhibition of p-450 aromatase prevents feminisation and induces protection during cysticercosis. Int J Parasitol. 2002 Oct;32(11):1379-87.
Smiles	N#CC1=CC=C(C2CCCC3=CN=CN23)C=C1.Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	CGS 16949A; (Rac)-FAD286 (hydrochloride)
Available
Product Description	Fadrozole hydrochloride (CGS 16949A) is a potent, selective and nonsteroidal inhibitor of aromatase with an IC50 of 6.4 nM.
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
Molecular Weight	259.73
Clinical Information	Launched
Solubility	DMSO : 100 mg/mL (ultrasonic; warming)\|H2O : 100 mg/mL (ultrasonic)
Isoform	Aromatase/CYP19A1
Pathway	Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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HY-14247-5mg-safety-datasheet.pdf