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Zileuton

Zileuton

€224.00

Excl. VAT

Item no.	HY-14164-100mg
Manufacturer	MedChem Express
CASRN	111406-87-2
Amount	100 mg
Category	Oncology Neuroscience Metabolism Cholesterol & Lipid Metabolism Neural Signaling Cardiovascular Research Thrombosis & Hemostasis Inhibitors & Compound Libraries Small Molecules By Organ Heart & Blood Cancer
Type	Inhibitors
Clone	N/A
Specific against	other
Purity	99.86
Formula	C11H12N2O2S
Citations	[1]Kuvibidila S, et al. Hydroxyurea and Zileuton Differentially Modulate Cell Proliferation and Interleukin-2 Secretion by Murine Spleen Cells: Possible Implication on the Immune Function and Risk of Pain Crisis in Patients with Sickle Cell Disease. Ochsner [2]Abueid L, et al. Inhibition of 5-lipoxygenase by zileuton in a rat model of myocardial infarction. Anatol J Cardiol. 2016 Nov 10 [3]Gounaris E, et al. Zileuton, 5-lipoxygenase inhibitor, acts as a chemopreventive agent in intestinal polyposis, by modulating polyp and systemic inflammation. PLoS One. 2015 Mar 6;10(3):e0121402
Smiles	CC(N(O)C(N)=O)C1=CC2=CC=CC=C2S1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	A 64077; Abbott 64077
Available
Product Description	Zileuton is a potent and selective inhibitor of 5-lipoxygenase with antiasthmatic properties.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
Molecular Weight	236.29
Clinical Information	Launched
Solubility	DMSO : 100 mg/mL (ultrasonic)
Isoform	5-LOX
Pathway	Apoptosis; Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-14164-100mg-safety-datasheet.pdf