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2-Deoxy-D-glucose

2-Deoxy-D-glucose

€59.00

Excl. VAT

Item no.	HY-13966-1g
Manufacturer	MedChem Express
CASRN	154-17-6
Amount	1 g
Category	Oncology Metabolism Diabetes Cholesterol & Lipid Metabolism Regulation of Appetite Inhibitors & Compound Libraries Small Molecules By Organ Breast Cancer
Type	Inhibitors
Clone	N/A
Specific against	other
Purity	99.93
Formula	C6H12O5
Citations	[1]Ueyama A, et al. Nonradioisotope assay of glucose uptake activity in rat skeletal muscle using enzymatic measurement of 2-deoxyglucose 6-phosphate in vitro and in vivo. Biol Signals Recept. 2000 Sep-Oct;9(5):267-74. [2]Zhu Z, et al. 2-Deoxyglucose as an energy restriction mimetic agent: effects on mammary carcinogenesis and on mammary tumor cell growth in vitro. Cancer Res. 2005 Aug 1;65(15):7023-30. [3]Miwa H, et al. Leukemia cells demonstrate a different metabolic perturbation provoked by 2-deoxyglucose. Oncol Rep. 2013 May;29(5):2053-7.
Smiles	OC1O[C@@H]([C@@H](O)[C@H](O)C1)CO
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	2-DG; 2-Deoxy-D-arabino-hexose; D-Arabino-2-deoxyhexose
Available
Product Description	2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-Kinase/protease
Molecular Weight	164.16
Clinical Information	Phase 2
Solubility	H2O : ≥ 24 mg/mL
Isoform	HSV-1
Pathway	Anti-infection; Apoptosis; Metabolic Enzyme/Protease
Manufacturers Product type	Natural Products

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HY-13966-1g-safety-datasheet.pdf