« Back
Home /
GANT 61

GANT 61

€72.00

Excl. VAT

Item no.	HY-13901-10mM
Manufacturer	MedChem Express
CASRN	500579-04-4
Amount	10 mM/1 mL
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Colorectal Cancer Breast Cancer Nervous System Cancer
Type	Inhibitors
Specific against	other
Purity	98.0
Formula	C27H35N5
Citations	[1]Fu J, et al. GANT-61 inhibits pancreatic cancer stem cell growth in vitro and in NOD/SCID/IL2R gamma null mice xenograft. Cancer Lett. 2013 Mar 1;330(1):22-32. [2]Mazumdar T, et al. Hedgehog signaling drives cellular survival in human colon carcinoma cells. Cancer Res. 2011 Feb 1;71(3):1092-102. [3]Wickstrom M, et al. Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro and in vivo. Int J Cancer. 2013 Apr 1;132(7):1516-24.
Smiles	CN(C)C1=CC=CC=C1CN2C(C3=CC=NC=C3)N(CC4=CC=CC=C4N(C)C)CCC2
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	NSC 136476
Available
Product Description	GANT 61 is an inhibitor of Gli1 and Gli2 targeting the Hedgehog/GLI pathway.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
Molecular Weight	429.60
Clinical Information	No Development Reported
Solubility	DMSO : 25 mg/mL (ultrasonic)\|Ethanol : 66.67 mg/mL (ultrasonic)
Pathway	Autophagy; Stem Cell/Wnt
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

HY-13901-10mM-safety-datasheet.pdf