SC-514

€60.00

Excl. VAT

Item no.	HY-13802-10mg
Manufacturer	MedChem Express
CASRN	354812-17-2
Amount	10 mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Breast Cancer
Type	Inhibitors
Specific against	other
Purity	99.89
Formula	C9H8N2OS2
Citations	[1]Kishore N, et al. A selective IKK-2 inhibitor blocks NF-kappa B-dependent gene expression in interleukin-1 beta-stimulated synovial fibroblasts. J Biol Chem. 2003 Aug 29;278(35):32861-71. [2]Tse AK, et al. Sensitization of melanoma cells to alkylating agent-induced DNA damage and cell death via orchestrating oxidative stress and IKKβ inhibition. Redox Biol. 2017 Apr;11:562-576.
Smiles	O=C(C1=C(N)C=C(C2=CSC=C2)S1)N
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	GK 01140
Available
Product Description	SC-514 is a selective IKK-2 inhibitor (IC50=11.2 μM), which does not inhibit other IKK isoforms or other serine-threonine and tyrosine kinases.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-Kinase/protease
Molecular Weight	224.30
Clinical Information	No Development Reported
Solubility	DMSO : 50 mg/mL (ultrasonic)
Isoform	IKK-β
Pathway	NF-κB
Manufacturers Product type	Reference compound

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HY-13802-10mg-safety-datasheet.pdf