Comparison

Isobavachalcone European Partner

€76.00
Excl. VAT
Item no. HY-13065-10mM
Manufacturer MedChem Express
CASRN 20784-50-3
Amount 10 mM/1 mL
Category
Type Inhibitors
Specific against other
Purity 99.01
Formula C20H20O4
Citations [1]Jing H, et al. Abrogation of Akt signaling by Isobavachalcone contributes to its anti-proliferative effects towards human cancer cells. Cancer Lett. 2010 Aug 28;294(2):167-77.
Smiles O=C(/C=C/C1=CC=C(C=C1)O)C2=CC=C(C(C/C=C(C)\C)=C2O)O
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias Corylifolinin; Isobacachalcone
Available
Product Description
Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 μM). Isobavachalcone also induces Reactive Oxyen Species (ROS) generation in OVCAR-8 cells and has exhibit cancer anti-promotive and anti-proliferative activity[1].
StorageTemperature
4°C (Powder, protect from light)
Shipping
Room Temperature
Manufacturers Applications
Cancer-Kinase/protease
Molecular Weight
324.37
Clinical Information
No Development Reported
Solubility
DMSO : 11 mg/mL (ultrasonic; warming)
Pathway
Apoptosis; Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; PI3K/Akt/mTOR
Manufacturers Product type
Natural Products

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 mM/1 mL
Available: In stock
Listprice: €76.00
Price: €76.00
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