S49076

€49.00

Excl. VAT

Item no.	HY-12965-2mg
Manufacturer	MedChem Express
CASRN	1265965-22-7
Amount	2 mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Lung Cancer Colorectal Cancer Gastric Cancer
Type	Inhibitors
Specific against	other
Purity	99.71
Formula	C22H22N4O4S
Citations	[1]Burbridge MF, et al. S49076 is a novel kinase inhibitor of MET, AXL, and FGFR with strong preclinical activity alone and in association with bevacizumab. Mol Cancer Ther. 2013 Sep;12(9):1749-62.
Smiles	O=C(N1CC2=CC3=C(NC(/C3=C\C4=CC(CN5CCOCC5)=CN4)=O)C=C2)SCC1=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1265965-22-7
Available
Product Description	S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3 with IC50 values below 20 nM.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-Kinase/protease
Molecular Weight	438.50
Clinical Information	No Development Reported
Solubility	DMSO : ≥ 31 mg/mL
Isoform	FGFR1; FGFR2; FGFR3
Pathway	Protein Tyrosine Kinase/RTK
Manufacturers Product type	Reference compound

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HY-12965-2mg-safety-datasheet.pdf