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CH-223191

CH-223191

€612.00

Excl. VAT

Item no.	HY-12684-100mg
Manufacturer	MedChem Express
CASRN	301326-22-7
Amount	100 mg
Category	Food Safety Vitamines Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Purity	99.60
Formula	C19H19N5O
Citations	[1]Kim SH, et al. Novel compound 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazo-phenyl)-amide (CH-223191) prevents 2,3,7,8-TCDD-induced toxicity by antagonizing the aryl hydrocarbon receptor. Mol Pharmacol. 2006 Jun;69(6):1871-8. Epub 2006 Mar 15.
Smiles	O=C(C1=CC=NN1C)NC2=CC=C(/N=N/C3=CC=CC=C3C)C=C2C
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	301326-22-7
Available
Product Description	CH-223191 is a potent and specific antagonist of aryl hydrocarbon receptor (AhR).CH-223191 inhibits TCDD-mediated nuclear translocation and DNA binding of AhR, and inhibits TCDD-induced luciferase activity with an IC50 of 0.03 μM[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
Molecular Weight	333.39
Clinical Information	No Development Reported
Solubility	DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Pathway	Immunology/Inflammation
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-12684-100mg-safety-datasheet.pdf