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LSZ-102

LSZ-102

€306.00

Excl. VAT

Item no.	HY-111486-10mM
Manufacturer	MedChem Express
CASRN	2135600-76-7
Amount	10 mM/1 mL
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.80
Formula	C25H17F3O4S
Citations	[1]Tria GS, et al. Discovery of LSZ102, a Potent, Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen Receptor Positive Breast Cancer. J Med Chem. 2018 Apr 12;61(7):2837-2864.
Smiles	O=C(O)/C=C/C1=CC=C(OC2=C(C3=CC=C(F)C=C3C(F)(F)C)SC4=CC(O)=CC=C42)C=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	2135600-76-7
Available
Product Description	LSZ-102 is a potent, orally bioavailable selective estrogen receptor degrader with an IC50 of 0.2 nM.
StorageTemperature	-20°C (Powder, stored under nitrogen)
Shipping	Blue Ice
Manufacturers Applications	Cancer-programmed cell death
Molecular Weight	470.46
Clinical Information	Phase 1
Solubility	DMSO : 100 mg/mL (ultrasonic)\|H2O : 2 mg/mL (ultrasonic)
Pathway	Vitamin D Related/Nuclear Receptor
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-111486-10mM-safety-datasheet.pdf