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5α-Pregnane-3β,6α-diol-20-one

5α-Pregnane-3β,6α-diol-20-one

€256.00

Excl. VAT

Item no.	HY-109564-10mg
Manufacturer	MedChem Express
CASRN	21853-11-2
Amount	10 mg
Category	Oncology Food Safety Hormones Inhibitors & Compound Libraries Small Molecules By Organ Testicular & Prostate Cancer
Type	Inhibitors
Specific against	other
Purity	98.0
Formula	C21H34O3
Citations	[1]Zhang J, et al. Progesterone metabolism in human fibroblasts is independent of P-glycoprotein levels and Niemann-Pick type C disease. J Steroid Biochem Mol Biol. 1999 Sep-Oct;70(4-6):123-31. [2]de Mello Martins AGG, et al. CYP17A1-independent production of the neurosteroid-derived 5α-pregnan-3β,6α-diol-20-one in androgen-responsive prostate cancer cell lines under serum starvation and inhibition by Abiraterone. J Steroid Biochem Mol Biol. 2017 Nov;174:183-191.
Smiles	C[C@@]12[C@]3([H])[C@](C[C@H](O)[C@@]1([H])C[C@@H](O)CC2)([H])[C@@]4([H])[C@@](C)([C@@H](C(C)=O)CC4)CC3
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	21853-11-2
Available
Product Description	5α-Pregnane-3β, 6α-diol-20-one is a mitogenic metabolite of progesterone, and it can be produced in starved androgen-responsive prostate cancer cells.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
Molecular Weight	334.49
Clinical Information	No Development Reported
Solubility	DMSO : 100 mg/mL (ultrasonic)
Pathway	Metabolic Enzyme/Protease
Manufacturers Product type	Natural Products

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HY-109564-10mg-safety-datasheet.pdf