KY1220

€39.00

Excl. VAT

Item no.	HY-102028-2mg
Manufacturer	MedChem Express
CASRN	292168-79-7
Amount	2 mg
Category	Oncology Neuroscience Molecular Targets for Neuroscience Neural Signaling Neural Adhesion Molecules Inhibitors & Compound Libraries Small Molecules By Organ Lung Cancer Colorectal Cancer Testicular & Prostate Cancer
Type	Inhibitors
Specific against	other
Purity	98.0
Formula	C14H10N4O3S
Citations	[1]Cha PH, et al. Small-molecule binding of the axin RGS domain promotes β-catenin and Ras degradation. Nat Chem Biol. 2016 Aug;12(8):593-600.
Smiles	O=C(/C(N1)=C/C2=CC=CN2C3=CC=C([N+]([O-])=O)C=C3)NC1=S
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	292168-79-7
Available
Product Description	KY1220 is a compound that destabilizes both β-catenin and Ras, via targeting the Wnt/β-catenin pathway; with an IC50 of 2.1 μM in HEK293 reporter cells.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
Molecular Weight	314.32
Clinical Information	No Development Reported
Solubility	DMSO : 50 mg/mL (ultrasonic)
Pathway	Stem Cell/Wnt
Manufacturers Product type	Reference compound

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HY-102028-2mg-safety-datasheet.pdf