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Acridine Orange hydrochloride

Acridine Orange hydrochloride

€65.00

Excl. VAT

Item no.	HY-101879-10mM
Manufacturer	MedChem Express
CASRN	65-61-2
Amount	10 mM/1 mL
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Heart & Blood Cancer Bone Cancer
Type	Inhibitors
Specific against	other
Purity	99.86
Formula	C17H20ClN3
Citations	Acta Pharm Sin B. 2021 Feb 11. Adv Funct Mater. 2023 Apr 14. Cell Death Dis. 2020 Jul 30;11(7):607. Cell Death Dis. 2021 Jan 13;12(1):80. Cell Prolif. 2021 Dec 24;e13172. Clin Transl Med. 2023 Mar;13(3):e1229. Environ Toxicol. 2023 May 20. Free Radic Biol Med. 2023 Sep 1;208:402-417. Int J Mol Med. 2023 Apr 7. Int J Mol Sci. 2023 Sep 5, 24(18), 13812. Microbiol Spectr. 2023 May 1;e0313822. Nat Commun. 2023 Jun 30;14(1):3877. SSRN. 2023 Mar 9. SSRN. 2023 Nov 15. Chemosphere. 2023 Apr;320:138071. Research Square Print. December 12th, 2022. [1]McMaster GK, et al. Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarosegels by using glyoxal and acridine orange. Proc Natl Acad Sci U S A. 1977 Nov;74(11):4835-8. [2]Traganos F, et al. Simultaneous staining of ribonucleic and deoxyribonucleic acids in unfixed cells using acridine orange in a flow cytofluorometric system. J Histochem Cytochem. 1977 Jan;25(1):46-56. [3]Byvaltsev VA, et al. Acridine Orange: A Review of Novel Applications for Surgical Cancer Imaging and Therapy. Front Oncol. 2019 Sep 24;9:925. [4]Wang Q, et al. Substrate stiffness regulates the differentiation profile and functions of osteoclasts via cytoskeletal arrangement. Cell Prolif. 2022 Jan;55(1):e13172.
Smiles	CN(C)C1=CC=C2C(N=C3C=C(N(C)C)C=CC3=C2)=C1.[H]Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	65-61-2
Available
Product Description	Acridine Orange hydrochloride is a cell-penetrable nucleic acid-selective fluorescent dye. Acridine Orange hydrochloride produces orange fluorescence when it binds to ssDNA or RNA, and green fluorescence when it binds to dsDNA (Ex: 488 nM; Em: green fluorescence at 530 nm, orange fluorescence at 640 nm)[1][2][3].
StorageTemperature	4°C (Powder, protect from light, stored under nitrogen)
Shipping	Room Temperature
Molecular Weight	301.81
Clinical Information	No Development Reported
Solubility	DMSO : 25 mg/mL (ultrasonic)\|H2O : 50 mg/mL (ultrasonic; heat to 60°C)
Pathway	Anti-infection; Cell Cycle/DNA Damage; Others
Manufacturers Product type	Dye Reagents

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HY-101879-10mM-safety-datasheet.pdf