BAPTA

€65.00

Excl. VAT

Item no.	HY-100168-10mM
Manufacturer	MedChem Express
CASRN	85233-19-8
Amount	10 mM/1 mL
Category	Cell Biology Cell Stainings Cardiovascular Research Ischemia & Reperfusion Injury Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.0
Formula	C22H24N2O10
Citations	[1]R Y Tsien, et al. New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures. Biochemistry. 1980 May 27;19(11):2396-404. [2]Roger C Hardie, et al. Inhibition of phospholipase C activity in Drosophila photoreceptors by 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid (BAPTA) and di-bromo BAPTA. Cell Calcium. 2005 Dec;38(6):547-56. [3]M B Collatz, et al. Intracellular calcium chelator BAPTA protects cells against toxic calcium overload but also alters physiological calcium responses. Cell Calcium
Smiles	O=C(O)CN(C1=CC=CC=C1OCCOC2=CC=CC=C2N(CC(O)=O)CC(O)=O)CC(O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	85233-19-8
Available
Product Description	BAPTA is a selective chelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA is widely used as an intracellular buffer for investigating the effects of Ca2+ release from intracellular stores or influx via Ca2+-permeable channels in the plasma membrane. BAPTA can also inhibit phospholipase C activity independently of their role as Ca2+ chelators[1][2].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Molecular Weight	476.43
Clinical Information	No Development Reported
Solubility	1M NaOH : 33.33 mg/mL (ultrasonic; adjust pH to 11 with NaOH)\|DMSO : 15.62 mg/mL (ultrasonic; warming; heat to 60°C)
Pathway	Metabolic Enzyme/Protease
Manufacturers Product type	Biochemical Assay Reagents

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HY-100168-10mM-safety-datasheet.pdf