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tri-GalNAc biotin

tri-GalNAc biotin

€3,444.00

Excl. VAT

Item no.	HY-147102-10mg
Manufacturer	MedChem Express
Amount	10 mg
Category	Other Assays & Kits Purification & Separation Kits
Type	Separation, Purification
Specific against	other
Purity	99.40
Formula	C83H146N14O34S
Citations	[1]Zhou Y, et al Development of Triantennary N-Acetylgalactosamine Conjugates as Degraders for Extracellular Proteins. ACS Cent Sci. 2021 Mar 24;7(3):499-506
Smiles	O=C(CCNC(CCOCCOCCOCCNC(CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O)=O)=O)NC(COCCC(NCCCNC(CCCCO[C@H](O[C@@H]3CO)[C@@H]([C@H]([C@H]3O)O)NC(C)=O)=O)=O)(COCCC(NCCCNC(CCCCO[C@H](O[C@@H]4CO)[C@@H]([C@H]([C@H]4O)O)NC(C)=O)=O)=O)COCCC(NCCCNC(CCCCO[C@H](O[C@@H]5CO)[C@@H]([C@H]([C@H]5O)O)NC(C)=O)=O)=O
ECLASS 10.1	32170301
ECLASS 11.0	32170301
UNSPSC	41104900
Available
Product Description	tri-GalNAc biotin is a small molecule lysosome targeting degrader. tri-GalNAc is a ligand of ASGPR (asialoglycoprotein receptor). tri-GalNAc biotin can facilitate the uptake of NeutrAvidin (NA) through ASGPR in liver cells. tri-GalNAc biotin delivers NeutrAvidin to lysosome for degradation. tri-GalNAc biotin can be used for research of LYsosome TArgeting Chimera (LYTAC)[1].
StorageTemperature	-20°C, 3 years (Powder)
Shipping	Blue Ice
Manufacturers Applications	Cancer-programmed cell death
Molecular Weight	1916.19
Clinical Information	No Development Reported
Solubility	DMSO : 100 mg/mL (ultrasonic)
Pathway	PROTAC
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 mg

Listprice: €3,444.00

Price: €3,444.00

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