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Regorafenib monohydrate

Regorafenib monohydrate

€34.00

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Item no.	TMO-T1792L-5mg
Manufacturer	TargetMol
CASRN	1019206-88-2
Amount	5mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.47%
Citations	Zopf D, et al. Pharmacologic activity and pharmacokinetics of metabolites of regorafenib in preclinical models. Cancer Med. 2016 Nov;5(11):3176-3185.
Smiles	O.CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)c(F)c2)ccn1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1019206-88-2
Available
Short Description	Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine VEGFR3, PDGFR-β, KIT, RET, RAF-1, B-RAF and B-RAF(V600E) respectively.
Shipping	cool pack
Storage	-20°
Molecular Weight	500, 83
Pathway	Autophagy\|\|\|Angiogenesis\|\|\|Tyrosine Kinase/Adaptors\|\|\|Apoptosis\|\|\|MAPK
Target	VEGFR\|\|\|c-RET\|\|\|Autophagy\|\|\|Raf\|\|\|PDGFR\|\|\|c-Kit

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5mg

Listprice: €34.00

Price: €34.00

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Delivery expected until 9/4/2025

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