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Inavolisib

Inavolisib

€1,900.00

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Item no.	M11405-50mg
Manufacturer	AbMole
CASRN	2060571-02-8
Amount	50mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	>98%
Formula	C18H19F2N5O4
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	GDC-0077; RG6114；RO-7113755
Available
Bioactivity information	GDC-0077 (RG6114) is a potential best-in-class, orally selective PI3Kα inhibitor (IC50=0.038 nM). GDC-0077 (RG6114) exerts its activity by binding to the ATP binding site of PI3K, thereby inhibiting the phosphorylation of PIP2 to PIP3. GDC-0077 (RG6114) is more selective for mutants compared to wild-type PI3Kα. It can trigger the degradation of mutation-producing PIK3α.
mw	407, 37
solubility	DMSO ≥ 60 mg/mL

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50mg

Listprice: €1,900.00

Price: €1,900.00

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Delivery expected until 9/11/2025

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