Comparison

Mitazalimab European Partner

€1,230.00
Excl. VAT
Item no. HY-P99742-10mg
Manufacturer MedChem Express
CASRN 2055640-86-1
Amount 10 mg
Category
Type Inhibitors
Specific against other
Purity 95.00
Dry ice Yes
Citations [1]Deronic A, et al. The human anti-CD40 agonist antibody mitazalimab (ADC-1013; JNJ-64457107) activates antigen-presenting cells, improves expansion of antigen-specific T cells, and enhances anti-tumor efficacy of a model cancer vaccine in vivo. Cancer Immunol Immunother. 2021 Dec;70(12):3629-3642.
[2]Smith K E, et al. Mitazalimab, a potent CD40 agonist in combination with chemotherapy redirects and activates tumor infiltrating myeloid cells[J]. Cancer Research, 2022, 82(12_Supplement): 4155-4155.
Smiles [Mitazalimab]
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias ADC-1013; JNJ-64457107
Available
Product Description
Mitazalimab (ADC-1013; JNJ-64457107) is FcγR-dependent CD40 agonist with tumor-directed activity. Mitazalimab activates antigen-presenting cells, e.g. dendritic cells (DC), to initiate tumor-reactive T cells. Therefore, Mitazalimab induces tumor-specific T cells to infiltrate and kill tumors. Mitazalimab remodels the tumor-infiltrating myeloid microenvironment[1][2].
StorageTemperature
Store at -80°C for 2 years
Shipping
Dry Ice
Molecular Weight
N/A
Clinical Information
Phase 2
Solubility
10 mM in DMSO
Isoform
TNFRSF5/CD40
Pathway
Apoptosis
Manufacturers Product type
Inhibitory Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 mg
Available: In stock
Listprice: €1,230.00
Price: €1,230.00
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