ACK1 Protein, Human (sf9, GST)

ACK1 Protein, a non-receptor tyrosine-protein and serine/threonine-protein kinase, orchestrates cell physiology by influencing cell spreading, migration, survival, growth, and proliferation. It phosphorylates AKT1, AR, MCF2, WASL, and WWOX, impacting various cellular processes. ACK1 participates in clathrin-mediated endocytosis, regulating ligand-induced EGFR degradation, and contributes to CDC42-dependent cell migration. It activates AKT1, phosphorylates AR, and enhances WWOX activity, influencing cancer progression by regulating metastasis and tumor growth. ACK1's diverse signaling capabilities extend to phosphorylating WASP, emphasizing its multifaceted role in cellular functions and oncogenic processes. ACK1 Protein, Human (sf9, GST) is the recombinant human-derived ACK1 protein, expressed by Sf9 insect cells, with N-GST labeled tag. The total length of ACK1 Protein, Human (sf9, GST) is 367 a.a., with molecular weight of ~62 kDa.

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Recombinant Proteins