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IL-27 Protein, Mouse (228a.a, HEK293, His)

IL-27 Protein, Mouse (228a.a, HEK293, His)

€133.00

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Item no.	HY-P73200-5ug
Manufacturer	MedChem Express
Amount	5 ug
Category	Inhibitors & Compound Libraries Small Molecules
Type	Peptides
Specific against	other
Purity	87.50
Dry ice	Yes
Citations	[1]Fabbi M, et al. Dual Roles of IL-27 in Cancer Biology and Immunotherapy. Mediators Inflamm. 2017;2017:3958069. [2][2]Kourko O, et al. IL-27, IL-30, and IL-35: A Cytokine Triumvirate in Cancer. Front Oncol. 2019 Oct 1;9:969. [3]Xu F, et al. IL-27 regulates the adherence, proliferation, and migration of MSCs and enhances their regulatory effects on Th1 and Th2 subset generations. Immunol Res. 2017 Aug;65(4):903-912. [4]Petes C, et al. IL-27 amplifies cytokine responses to Gram-negative bacterial products and Salmonella typhimurium infection. Sci Rep. 2018 Sep 12;8(1):13704. [5]Pflanz S, et al. IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells. Immunity. 2002 Jun;16(6):779-90. [6][7]Seita J, et al. Interleukin-27 directly induces differentiation in hematopoietic stem cells. Blood. 2008 Feb 15;111(4):1903-12. [7]Hanson ML, et al. Oral delivery of IL-27 recombinant bacteria attenuates immune colitis in mice. Gastroenterology. 2014 Jan;146(1):210-221.e13. [8]Qi J, et al. IL-27 Regulated CD4+IL-10+ T Cells in Experimental Sjögren Syndrome. Front Immunol. 2020 Aug 11;11:1699.
Smiles	YTETALVALS QPRVQCHASR YPVAVDCSWT PLQAPNSTRS TSFIATYRLG VATQQQSQPC LQRSPQASRC TIPDVHLFST VPYMLNVTAV HPGGASSSLL AFVAERIIKP DPPEGVRLRT AGQRLQVLWH PPASWPFPDI FSLKYRLRYR RRGASHFRQV GPIEATTFTL RNSKPHAKYC IQVSAQDLTD YGKPSDWSLP GQVESAPHKP GSGSGGSGGS GSGKLFPTDP LSLQELRREF TVSLYLARKL LSEVQGYVHS FAESRLPGVN LDLLPLGYHL PNVSLTFQAW HHLSDSERLC FLATTLRPFP AMLGGLGTQG TWTSSEREQL WAMRLDLRDL HRHLRFQVLA AGFKCSKEEE DKEEEEEEEE EEKKLPLGAL GGPNQVSSQV SWPQLLYTYQ LLHSLELVLS RAVRDLLLLS LPRRPGSAWD S
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	IL-27 Protein, Mouse (228a.a, HEK293, His),Mouse,HEK293
Available
Product Description	IL-27 (Interleukin-27) is a heterodimeric cytokine of the IL-12 family, composed of two subunits, EBI3 (Epstein-Barr-virus-induced molecule 3) and p28[1]. IL-27 enhances the development, proliferation, and cytotoxic activity of CD8+ T cells, thereby indirectly promoting anti-tumor immunity[ 2]. IL-27 Protein, Mouse (228a.a, HEK293, His) is a recombinant protein with a His label that consists of two subunits, EBI3 (IL27B) (228 amino acids (M1-P228)) and IL27A (205 amino acids (F29-S234)), and is produced by HEK293 cells.
StorageTemperature	Stored at -20°C for 2 years
Shipping	Dry Ice
Molecular Weight	Approximately 60 kDa
Manufacturers Product type	Recombinant Proteins

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5 ug

Listprice: €133.00

Price: €133.00

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