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Musk ketone

Musk ketone

€39.00

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Item no.	HY-N2045-100mg
Manufacturer	MedChem Express
CASRN	81-14-1
Amount	100 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.41
Formula	C14H18N2O5
Citations	[1]Yamagishi T, et al. Identification of musk xylene and musk ketone in freshwater fish collected from the Tama River, Tokyo. Bull Environ Contam Toxicol. 1981 May;26(5):656-62. [2]Mersch-Sundermann V, et al. Musk ketone enhances benzo(a)pyrene induced mutagenicity in human derived Hep G2 cells. Mutat Res. 2001 Aug 22;495(1-2):89-96. [3]Zhou Z, et al. Musk Ketone Induces Neural Stem Cell Proliferation and Differentiation in Cerebral Ischemia via Activation of the PI3K/Akt Signaling Pathway. Neuroscience. 2020 May 21;435:1-9. [4]Lehman-McKeeman LD, et al. Effects of musk xylene and musk ketone on rat hepatic cytochrome P450 enzymes. Toxicol Lett. 1999 Dec 20;111(1-2):105-15. [5]An J, et al. Musk ketone induces apoptosis of gastric cancer cells via downregulation of sorbin and SH3 domain containing 2. Mol Med Rep. 2021 Jun;23(6):450.
Smiles	CC(C1=C(C)C([N+]([O-])=O)=C(C(C)(C)C)C([N+]([O-])=O)=C1C)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	Musk ketone is a widely used artificial fragrance. Musk ketone is also a cytochrome P450 enzyme inducer. Musk ketone shows mutagenic and comutagenic effects in Hep G2 cells and induces neural stem cell proliferation and differentiation in cerebral ischemia via activation of the PI3K/Akt signaling pathway. In the brain, musk ketone is neuroprotective against stroke injury through inhibition of cell apoptosis[1][2][3].
StorageTemperature	-20°C (Powder, sealed storage, away from moisture and light)
Shipping	Blue Ice
Manufacturers Applications	Neuroscience-Neurodegeneration
Molecular Weight	294.30
Clinical Information	No Development Reported
Solubility	DMSO : ≥ 125 mg/mL
Pathway	Apoptosis; Metabolic Enzyme/Protease; PI3K/Akt/mTOR
Manufacturers Product type	Natural Products

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

Listprice: €39.00

Price: €39.00

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