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2-Thiouracil

2-Thiouracil

€25.00

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Item no.	HY-B0503-500mg
Manufacturer	MedChem Express
CASRN	141-90-2
Amount	500 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.87
Formula	C4H4N2OS
Citations	[1]Palumbo, A., et al. 2-thiouracil is a selective inhibitor of neuronal nitric oxide synthase antagonising tetrahydrobiopterin-dependent enzyme activation and dimerisation. FEBS Lett, 2000. 485(2-3): p. 109-12. [2]Napolitano, A., et al., Mechanism of selective incorporation of the melanoma seeker 2-thiouracil into growing melanin. J Med Chem, 1996. 39(26): p. 5192-201.
Smiles	O=C(C=CN1)NC1=S
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Thiouracil
Available
Product Description	2-Thiouracil (Thiouracil) is an antithyroid compound. 2-Thiouracil can function as a highly specific melanoma seeker. 2-Thiouracil is a selective inhibitor of neuronal nitric oxide synthase (nNOS) with a Ki of 20 μM[1][2].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
Molecular Weight	128.15
Clinical Information	No Development Reported
Solubility	DMSO : 50 mg/mL (ultrasonic)\|H2O : 0.67 mg/mL (ultrasonic)
Isoform	nNOS
Pathway	Immunology/Inflammation
Manufacturers Product type	Reference compound

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HY-B0503-500mg-safety-datasheet.pdf