Comparison

Galidesivir (hydrochloride) European Partner

€3,030.00
Excl. VAT
Item no. HY-18649-50mg
Manufacturer MedChem Express
CASRN 222631-44-9
Amount 50 mg
Category
Type Inhibitors
Specific against other
Purity 99.89
Formula C11H16ClN5O3
Citations Antimicrob Agents Chemother. 2019 Feb 26;63(3):e02093-18.
Antiviral Res. 2017 Mar 21;142:63-67.
Nucleic Acids Res. 2021 Jan 8;49(D1):D1113-D1121.
Antiviral Res. 2017 Mar 21;142:63-67.
Exp Ther Med. 2016 Sep;12(3):1812-1816.
Microorganisms. 2021 Mar 31;9(4):734.
Nucleic Acids Res. 2021 Jan 8;49(D1):D1113-D1121.
Virology. 2023 May 26.
Viruses. 2020 Jun 10;12(6):628.
[1]Elfiky AA, et al. ICN-1229, Remdesivir, PSI-7977, Galidesivir, and GS 1278 against SARS-CoV-2 RNA dependent RNA polymerase (RdRp): A molecular docking study. Life Sci. 2020 Mar 25:117592.
[2]Taylor R, et al. BCX4430 - A broad-spectrum antiviral adenosine nucleoside analog under development for the treatment of Ebola virus disease. J Infect Public Health. 2016;9(3):220-226.
[3]Warren TK, et al. Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430. Nature. 2014;508(7496):402-405.
[4]Julander JG, et al. BCX4430, a novel nucleoside analog, effectively treats yellow fever in a Hamster model. Antimicrob Agents Chemother. 2014;58(11):6607-6614.
Smiles O[C@H]1[C@H](C2=CNC3=C2N=CN=C3N)N[C@H](CO)[C@H]1O.Cl
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias BCX4430 (hydrochloride); Immucillin-A (hydrochloride)
Available
Product Description
Galidesivir (BCX4430) hydrochloride, an adenosine analog and a direct-acting antiviral agent, disrupts viral RNA-dependent RNA polymerase (RdRp) activity. Galidesivir hydrochloride is active in vitro against many RNA viral pathogens, including the filoviruses and emerging infectious agents such as MERS-CoV, SARS-CoV, and SARS-CoV-2. Galidesivir hydrochloride inhibits some negative-sense RNA viruses with EC50s ranging from ~3 to ~68 μM[1][2][3].
StorageTemperature
4°C (Powder, sealed storage, away from moisture)
Shipping
Room Temperature
Manufacturers Applications
COVID-19-anti-virus
Molecular Weight
301.73
Clinical Information
Phase 1
Solubility
DMSO : 105 mg/mL (ultrasonic)|H2O : ≥ 41 mg/mL
Pathway
Anti-infection; Cell Cycle/DNA Damage
Manufacturers Product type
Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 mg
Available: In stock
Listprice: €3,030.00
Price: €3,030.00
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