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BMS-767778

BMS-767778

Item no.	HY-16656
Manufacturer	MedChem Express
CASRN	915729-95-2
Amount	1 ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Formula	C19H20Cl2N4O2
Citations	[1]Pratik Devasthale, et al. Optimization of activity, selectivity, and liability profiles in 5-oxopyrrolopyridine DPP4 inhibitors leading to clinical candidate (Sa)-2-(3-(aminomethyl)-4-(2,4-dichlorophenyl)-2-methyl-5-oxo-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)-N,N-dimethylacetamide (BMS-767778). J Med Chem . 2013 Sep 26;56(18):7343-57.
Smiles	O=C(N(C)C)CN1CC2=NC(C)=C(CN)[C@]([C@]3=CC=C(Cl)C=C3Cl)=C2C1=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	BMS-767778 is a selective DPP4 inhibitor, with a Ki of 0.9 nM[1].
Shipping	Room temperature
Molecular Weight	407.29
Clinical Information	No Development Reported
Solubility	10 mM in DMSO
Pathway	Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

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