Comparison

ITF 3756 European Partner

€767.00
Excl. VAT
Item no. HY-156850-25mg
Manufacturer MedChem Express
CASRN 2247608-27-9
Amount 25 mg
Category
Type Inhibitors
Specific against other
Purity 98.55
Formula C13H11N5O2S
Citations [1]Gianluca Fossati, et al. Abstract 1358: The selective HDAC6 inhibitor ITF3756 stimulates an antitumor immune response and leads to tumor regression in combination with anti CTLA-4 antibody in a colon carcinoma murine model. Cancer Res (2022) 82 (12_Supplement): 1358.
Smiles O=C(C1=CC=C(CN2N=NN=C2C3=CC=CS3)C=C1)NO
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Product Description
ITF 3756 is a potent and selective HDAC6 inhibitor. ITF 3756 reduces in vitro the expression of PD-L1 on human monocytes and on CD8 T cells, and shows anti-tumor activity[1].
StorageTemperature
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping
Room Temperature
Molecular Weight
301.32
Clinical Information
No Development Reported
Solubility
DMSO : 125 mg/mL (ultrasonic)
Pathway
Cell Cycle/DNA Damage; Epigenetics
Manufacturers Product type
Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 25 mg
Available: In stock
Listprice: €767.00
Price: €767.00
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