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FPR2 agonist 3

FPR2 agonist 3

Item no.	HY-155335
Manufacturer	MedChem Express
CASRN	2829263-19-4
Amount	1 ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Formula	C25H20F2N4O2
Citations	[1]Jie Zang, et al. Targeting NOX2 with Bivalent Small-Molecule p47phox-p22phox Inhibitors. J Med Chem. 2023.
Smiles	FC1=CC=C(NC(N[C@@H](CC2=CC=C(C#N)C=C2)C(N3C(C=C(F)C=C4)=C4CC3)=O)=O)C=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	FPR2 agonist 3 (compound CMC23) can limit the lactate dehydrogenase release in LPS (HY-D1056) -stimulated cultures and decrease the levels of pro-inflammatory IL-1β and IL-6. FPR2 agonist 3 decrease the level of phosphor-STAT3 via the STAT3/SOCS3 signaling pathway[1].
Shipping	Room temperature
Molecular Weight	446.45
Clinical Information	No Development Reported
Solubility	10 mM in DMSO
Pathway	GPCR/G Protein
Manufacturers Product type	Reference compound

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