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DPP-4-IN-8

DPP-4-IN-8

Item no.	HY-155027
Manufacturer	MedChem Express
Amount	1 ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Formula	C16H12ClNO6
Citations	[1]Li CQ, et al. Licochalcone A Derivatives as Selective Dipeptidyl Peptidase 4 Inhibitors with Anti-Inflammatory Effects. J Nat Prod. 2023 Jul 28;86(7):1824-1831.
Smiles	[O-][N+](C1=CC(C(/C=C/C2=C(OC)C=C(O)C(Cl)=C2)=O)=CC=C1O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	DPP-4-IN-8 (compound 27) is a potent and selective DPP4 (dipeptidyl peptidase 4) inhibitor, with a Ki of 0.96 μM. DPP-4-IN-8 blocks the dipeptidase activity of DPP4 in both Caco-2 and HepG-2 cells. DPP-4-IN-8 also dose-dependently suppresses the expression levels of the chemokines tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and interleukin-1β (IL-1β)[1].
Shipping	Room temperature
Molecular Weight	349.72
Clinical Information	No Development Reported
Solubility	10 mM in DMSO
Isoform	DPP-4; IL-1; IL-6
Pathway	Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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