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GLX481304

GLX481304

Item no.	HY-153977-1ea
Manufacturer	MedChem Express
CASRN	701224-63-7
Amount	1 ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Formula	C23H29N7O
Citations	[1]Szekeres FLM, et al. A small molecule inhibitor of Nox2 and Nox4 improves contractile function after ischemia-reperfusion in the mouse heart. Sci Rep. 2021 Jun 7;11(1):11970.
Smiles	CC1=CC(NC2=NC(N)=NC(CN3CCN(CC3)C4=CC(OC)=CC=C4)=N2)=CC=C1C
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	GLX481304 is a specific inhibitor of Nox-2 and -4, with IC50s of 1.25 μM. GLX481304 suppresses ROS production in isolated mouse cardiomyocytes and improves cardiomyocyte contractility. GLX481304 can be used for research of ischemic injury to the heart[1].
StorageTemperature	4°C (Powder, protect from light)
Shipping	Room Temperature
Molecular Weight	419.52
Clinical Information	No Development Reported
Solubility	10 mM in DMSO
Pathway	Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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