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Cofrogliptin

Cofrogliptin

€344.00

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Item no.	HY-147257-5mg
Manufacturer	MedChem Express
CASRN	1844874-26-5
Amount	5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.07
Formula	C18H19F5N4O3S
Citations	[1]International Nonproprietary Names for Pharmaceutical Substances (INN) [2]Chen Zhang, et al. Design, Synthesis, and Evaluation of a Series of Novel Super Long-Acting DPP-4 Inhibitors for the Treatment of Type 2 Diabetes. J Med Chem. 2020 Jul 9;63(13):7108-7126.
Smiles	FC(F)([C@@H](O[C@]1([H])C(C=C2F)=C(C=C2)F)[C@@](N(CC3=N4)CC3=CN4[S](C)(=O)=O)([H])C[C@@H]1N)F
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	HSK7653
Available
Product Description	Cofrogliptin (HSK7653) (compound 2), a tetrahydropyran derivative, is a potent oral dipeptidyl aminopeptidase 4 (DPP-4) inhibitor with Long-acting antidiabetic efficacy. Cofrogliptin (compound 2) has a great potential for type 2 diabetes mellitus (T2DM) [1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Metabolism-protein/nucleotide metabolism
Molecular Weight	466.43
Clinical Information	Phase 3
Solubility	DMSO : 100 mg/mL (ultrasonic)
Isoform	DPP-4
Pathway	Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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Amount: 5 mg

Listprice: €344.00

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