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DPP-4 inhibitor 3

DPP-4 inhibitor 3

Item no.	HY-146455-1ea
Manufacturer	MedChem Express
CASRN	2402735-14-0
Amount	1 ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Formula	C19H22N6O2
Citations	[1]Bindu B, et al. Synthesis and discovery of triazolo-pyridazine-6-yl-substituted piperazines as effective anti-diabetic drugs; evaluated over dipeptidyl peptidase-4 inhibition mechanism and insulinotropic activities. Eur J Med Chem. 2020 Feb 1;187:111912.
Smiles	CCOC(N1CCN(CC1)C2=NN3C(C=C2)=NN=C3C4=CC=CC(C)=C4)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	DPP-4-IN-3 (Compound 5a) is a potent dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 0.75 nM. DPP-4-IN-3 shows excellent antioxidant and insulinotropic activity[1].
Shipping	Room temperature
Manufacturers Applications	Metabolism-protein/nucleotide metabolism
Molecular Weight	366.42
Clinical Information	No Development Reported
Solubility	10 mM in DMSO
Isoform	DPP-4
Pathway	Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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