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Rintodestrant

Rintodestrant

€2,558.00

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Item no.	HY-137449-50mg
Manufacturer	MedChem Express
CASRN	2088518-51-6
Amount	50 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	99.79
Formula	C26H19FO5S
Citations	[1]Kaitlyn J Andreano, et al. G1T48, an oral selective estrogen receptor degrader, and the CDK4/6 inhibitor lerociclib inhibit tumor growth in animal models of endocrine-resistant breast cancer. Breast Cancer Res Treat. 2020 Apr;180(3):635-646.
Smiles	O=C(C(C(C)=CC(F)=C1)=C1C)C(SC2=C3)=C(C2=CC=C3O)OC(C=C4)=CC=C4/C=C/C(O)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	G1T48
Available
Product Description	Rintodestrant (G1T48) is an orally active, non-steroidal and selective estrogen receptor degrader. Rintodestrant (G1T48) is also a CDK4/6 inhibitor[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-Kinase/protease
Molecular Weight	462.49
Clinical Information	Phase 1
Solubility	DMSO : 50 mg/mL (ultrasonic)
Pathway	Cell Cycle/DNA Damage; Vitamin D Related/Nuclear Receptor
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 mg

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