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MC-betaglucuronide-MMAE-1

MC-betaglucuronide-MMAE-1

€512.00

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Item no.	HY-136317-1mg
Manufacturer	MedChem Express
CASRN	1703778-92-0
Amount	1 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	99.72
Formula	C66H98N8O20
Citations	[1]Okeley, et al. Intracellular Activation of SGN-35, a Potent Anti-CD30 Antibody-Drug Conjugate. Clinical Cancer Research (2010), 16(3), 888-897.
Smiles	O[C@H]1[C@H](O)[C@@H](O)[C@H](OC2=C(NC(CCNC(CCCCCN3C(C=CC3=O)=O)=O)=O)C=C(COC(N(C)[C@@H](C(C)C)C(N[C@H](C(N(C)[C@@H]([C@H](CC)C)[C@H](OC)CC(N4[C@H]([C@H](OC)[C@@H](C)C(N[C@H](C)[C@@H](O)C5=CC=CC=C5)=O)CCC4)=O)=O)C(C)C)=O)=O)C=C2)O[C@@H]1C(O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	MC-betaglucuronide-MMAE-1 is a agent-linker conjugate for ADC with potent antitumor activity by using MMAE (a tubulin polymerization inhibitor), linked via the cleavable ADC linker MC-betaglucuronide.
StorageTemperature	-20°C (Powder, protect from light)
Shipping	Blue Ice
Manufacturers Applications	Cancer-programmed cell death
Molecular Weight	1323.53
Clinical Information	No Development Reported
Solubility	DMSO : 200 mg/mL (ultrasonic)
Isoform	Auristatin
Pathway	Antibody-drug Conjugate/ADC Related
Manufacturers Product type	ADC Related

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mg

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