Comparison

KRAS G12C inhibitor 15 European Partner

€7,871.00
Excl. VAT
Item no. HY-125873-100mg
Manufacturer MedChem Express
CASRN 2349393-21-9
Amount 100 mg
Category
Type Inhibitors
Specific against other
Purity 99.55
Formula C25H21ClF2N4O3
Citations [1]Jason Grant Kettle, et al. Tetracyclic compounds as inhibitors of g12c mutant ras protein, for use as anti-cancer agents. WO2019110751A1.
Smiles FC1=C(N=CC(N2C)=C3N4[C@H](CN(C(C=C)=O)[C@H](C)C4)C2=O)C3=CC(Cl)=[C@@]1[C@@]5=C(F)C=CC=C5O
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Product Description
KRAS G12C inhibitor 15 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 22, has an IC50 of 5 nM[1].
StorageTemperature
-20°C (Powder, protect from light, stored under nitrogen)
Shipping
Blue Ice
Manufacturers Applications
Cancer-Kinase/protease
Molecular Weight
498.91
Clinical Information
No Development Reported
Solubility
DMSO : 193.33 mg/mL (ultrasonic)
Isoform
K-Ras
Pathway
GPCR/G Protein; MAPK/ERK Pathway
Manufacturers Product type
Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 mg
Available: In stock
Listprice: €7,871.00
Price: €7,871.00
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