« Back
Home /
BRD6989

BRD6989

€87.00

Excl. VAT

Item no.	HY-122586-5mg
Manufacturer	MedChem Express
CASRN	642008-81-9
Amount	5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.56
Formula	C16H16N4
Citations	[1]Johannessen L, et al. Small-molecule studies identify CDK8 as a regulator of IL-10 in myeloid cells. Nat Chem Biol. 2017 Oct;13(10):1102-1108
Smiles	N#CC1=C(C2=CC=CN=C2)C3=C(N=C1N)CCC(C)C3
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	642008-81-9
Similar products	642008-81-9
Available
Product Description	BRD6989, an analog of the natural product cortistatin A (dCA), inhibits CDK8 and upregulates IL-10. BRD6989 selectively binds a complex of CDK8 with an IC50 of ~200 nM. BRD6989 inhibits the kinase activity of recombinant CDK8 or CDK19 complexes[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-anti-virus
Molecular Weight	264.33
Clinical Information	No Development Reported
Solubility	DMSO : 25 mg/mL (ultrasonic)
Isoform	CDK19; CDK8; IL-10
Pathway	Cell Cycle/DNA Damage; Immunology/Inflammation
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 5 mg

Listprice: €87.00

Price: €87.00

available

Quantity:

Compare

Add to wishlist