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NF546 (hydrate)

NF546 (hydrate)

€246.00

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Item no.	HY-108661A-1mg
Manufacturer	MedChem Express
Amount	1 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	97.0
Formula	C47H44N6Na4O17P4.13.5H20
Citations	[1]Meis S, et al. NF546 [4,4'-(carbonylbis(imino-3,1-phenylene-carbonylimino-3,1-(4-methyl-phenylene)-carbonylimino))-bis(1,3-xylene-alpha,alpha'-diphosphonic acid) tetrasodium salt] is a non-nucleotide P2Y11 agonist and stimulates release of interleukin-8 from human monocyte-derived dendritic cells. J Pharmacol Exp Ther. 2010 Jan;332(1):238-47.
Smiles	O=P(O)(O[Na])CC1=C(C=CC(CP(O)(O[Na])=O)=C1)NC(C2=CC(NC(C3=CC(NC(NC4=CC(C(NC5=CC(C(NC6=C(C=C(CP(O)(O[Na])=O)C=C6)CP(O)(O[Na])=O)=O)=CC=C5C)=O)=CC=C4)=O)=CC=C3)=O)=C(C)C=C2)=O.[13.5].O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	NF546 (hydrate) is a selective non-nucleotide P2Y11 agonist with a pEC50 of 6.27. NF546 (hydrate) stimulates release of interleukin-8 from human monocyte-derived dendritic cells[1].
StorageTemperature	-20°C (Powder, sealed storage, away from moisture)
Shipping	Blue Ice
Molecular Weight	1424.01
Clinical Information	No Development Reported
Solubility	10 mM in DMSO
Pathway	GPCR/G Protein
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mg

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