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Dutogliptin tartrate

Dutogliptin tartrate

Item no.	HY-10286A-1ea
Manufacturer	MedChem Express
CASRN	890402-81-0
Amount	1 ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Formula	C14H26BN3O9
Citations	[1]Marier JF, et al. Population pharmacokinetic analysis of dutogliptin, a selective dipeptidyl peptidase-4 inhibitor. Clin Pharmacol Drug Dev. 2014 Jul;3(4):297-304. [2]Pattzi HM, et al. Dutogliptin, a selective DPP4 inhibitor, improves glycaemic control in patients with type 2 diabetes: a 12-week, double-blind, randomized, placebo-controlled, multicentre trial. Diabetes Obes Metab. 2010 Apr;12(4):348-55.
Smiles	O=C(CN[C@@H]1CCNC1)N(CCC2)[C@@H]2B(O)O.O[C@H]([C@H](C(O)=O)O)C(O)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	PHX-1149
Available
Product Description	Dutogliptin tartrate (PHX-1149) is an orally available, potent, and selective dipeptidyl peptidase-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.
Shipping	Room temperature
Manufacturers Applications	Metabolism-protein/nucleotide metabolism
Molecular Weight	391.18
Clinical Information	Phase 3
Solubility	10 mM in DMSO
Isoform	DPP-4
Pathway	Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

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