VIMENTIN

GWB-91BB16

IgG1

Vimentin purified from porcine eye lens

This product recognises vimentin a 57kD molecule that forms part of the cytoskeleton of non-epithelial cells. It is expressed by a range of cell types including smooth muscle cells from blood vessel walls astrocytes and various cell lines. The antibody may be used to recognise tumours of mesenchymal origin such as sarcoma and lymphoma. Clone V9 is reported as being suitable for use in Western blotting (6). We have not confirmed this work.

Phosphate buffered saline

Suggested

Belongs to the intermediate filament family. 1. Heid. H. W. et al. (1988) Patterns of expression of trichocytic and epithelial cytokeratins in mammalian tissues. I. Human and bovine hair follicles. 2. Joling. P. et al. (1996) Immunohistochemical demonstration of cellular antigens of the cat by anti-human antibodies. Vet. Immunol. Immunopathol. 53: 115-127. 3. Komuro. T. et al. (1996) Anti-c-Kit protein immunoreactive cells corresponding to the interstitial cells of Cajal in the guinea-pig small intestine. 4. Ando. H. et al. (1999) Cardiac microvascular endothelial cells express alpha-smooth muscle actin and show low NOS III activity. 5. Josephsen. K. et al. (1999) Selective but nonspecific immunolabelling of enamel protein-associated compartments by a monoclonal antibody against vimentin. 6. Sanderson. J. et al. (2000) A human lens model of cortical cataract: Ca2+-induced protein loss. vimentin cleavage and opacification. 7. Fujimura. Y. et al. (2001) A new marker for cup cells in the rabbit small intestine: expression of vimentin intermediate filament protein.