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CD10 [56C6] (ready-to-use)

CD10 [56C6] (ready-to-use)

Item no.	20-272-191410
Manufacturer	GENWAY
Amount	6 ml
Category	Oncology Antibodies Immunohistochemistry Primary Antibodies By Organ Renal Cancer
Type	Antibody
Applications	IHC
Clone	56C6
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-A402D0
Similar products	20-272-191410
Available
Genway ID:	GWB-A402D0
Clone:	56C6
Isotype:	IgG1
Immunogen:	Prokaryotic recombinant protein corresponding to the external domain of the CD10 glycoprotein.
Positive Control:	Tonsil
Target:	CD10
Localization:	Type II membrane protein. Storage
Preservative:	Sodium Azide. Constituents: Tissue culture supernatant
Application Note:	IHC-P: Prediluted ready to use. Perform heat mediated antigen retrieval with 10 mM Citrate buffer pH 6. 0 prior to immunostaining before commencing with IHC staining protocol. IHC-Fr: Prediluted ready to use. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. Cellular
Localization:	Type II membrane protein. The CD10 antigen has been identified on the surface of early lymphoid progenitor cells immature B cells with in adult bone marrow and germinal center B cells within lymphoid tissue.
Function:	Thermolysin-like specificity but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Involved in the degradation of atrial natriuretic factor (ANF).
Catalytic Activity:	Preferential cleavage of polypeptides between hydrophobic residues particularly with Phe or Tyr at P1\' . Cofactor: Binds 1 zinc ion per subunit.
Enzyme Regulation:	Inhibited in a dose dependent manner by opiorphin.
Subcellular Location:	Membrane; Single-pass type II membrane protein.
Disease:	Important cell surface marker in the diagnostic of human acute lymphocytic leukemia.
Similarity:	Belongs to the peptidase M13 family [view classification].

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 6 ml

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Delivery expected until 9/11/2025

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