Synaptophysin (ready-to-use)

GWB-291C23

Human

Synaptophysin

This antibody has been pretitered and quality controlled to work on formalin-fixed paraffin-embedded as well as acetone fixed cryostat tissue sections. No further titration is required. We suggest an incubation period of 30 minutes at room temperature. However depending upon the fixation conditions and the staining system employed optimal incubation conditions should be determined by the user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer pH 6. 0 prior to immunostaining. Cellular

Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane.

Cytoplasmic vesicle secretory vesicle synaptic vesicle membrane; Multi-pass membrane protein. Cell junction synapse synaptosome.

The calcium-binding activity is thought to be localized in the cytoplasmic tail of the protein.

Belongs to the synaptophysin/synaptobrevin family.