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IRL-1038

IRL-1038

Item no.	RP13496
Manufacturer	GenScript
Amount	0.2mg
Category	Oncology Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders By Cell Type Melanoma Peptides & Proteins Cell Biology Cell Stainings Membrane Peptides By Organ Skin Cancer
Type	Peptides
Purity	> 95%
Sequence	CVYFCHLDIIW ; {CYS}{VAL}{TYR}{PHE}{CYS}{HIS}{LEU}{ASP}{ILE}{ILE}{TRP}
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	peptide/RP13496-IRL-1038, IRL 1038 is a novel antagonist of the ETB receptor responsible for the release of relaxing factor from the vascular endothelium. The ETB antagonist, IRL-1038, potentiated contractile responses to SRTX-c. </td></tr><tr><th>Solubility</th><td colspan="7"> Insoluble in water. Dissolve the content with 50-100 ml DMSO - then dilute to any desired concentration with water or buffer. </td></tr><tr><th>Purity</th><td colspan="7"> > 95% </td></tr><tr><th>Storage</th><td colspan="7"> Store at -20C. </td></tr><tr><th>Notes</th><td colspan="7"> 3 uM IRL-1038 antagonized the ETB receptor mediated contraction on guinea pig ileal and tracheal smooth muscle without any significant agonistic activity but did not affect the ETA receptor mediated contraction of rat aortic smooth muscle.</td></tr>
Available
Chemical Bridge	Disulfide bridge: Cys1-Cys5
Description	IRL 1038 is a novel antagonist of the ETB receptor responsible for the release of relaxing factor from the vascular endothelium. The ETB antagonist, IRL-1038, potentiated contractile responses to SRTX-c.
Notes	3 uM IRL-1038 antagonized the ETB receptor mediated contraction on guinea pig ileal and tracheal smooth muscle without any significant agonistic activity but did not affect the ETA receptor mediated contraction of rat aortic smooth muscle.
Solubility	Insoluble in water. Dissolve the content with 50-100 ml DMSO - then dilute to any desired concentration with water or buffer.
Storage	Store at -20C.
Product Origin	USA

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.2mg

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Delivery expected until 7/31/2025

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