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CHO-K1/mouse TIGIT Stable Cell Line

CHO-K1/mouse TIGIT Stable Cell Line

€8,500.00

Excl. VAT

Item no.	M00585
Manufacturer	GenScript
Amount	2 vials
Category	Neuroscience Neural Lineage Markers Neuroinflammation Neural Adhesion Molecules Cell Lines & Cell Culture Cell Lines
Type	Cell line
Specific against	Mouse (Murine, Mus musculus)
Dry ice	Yes
ECLASS 10.1	42040401
ECLASS 11.0	42040401
UNSPSC	41106509
Available
Description	TIGIT (also called T cell immunoreceptor with Ig and ITIM domains) is one newly discovered immune receptor on some percentage of T cells and Natural Killer Cells (NK). It is also identified as WUCAM and Vstm3. TIGIT binds to CD155 (PVR) on dendritic cells (DCs), macrophages, etc. with high affinity, and also to CD112 (PVRL2) with lower affinity. Research has shown that TIGIT-Fc fusion proteins interact with PVR on dendritic cells and increase IL-10 secretion, while decreasing IL-12 secretion under LPS stimulation. TIGIT-Fc fusion proteins also inhibit T cell activation in vivo. TIGIT's inhibition of NK cytotoxicity can be blocked by antibodies against its interaction with PVR, which is directed through its ITIM domain.
Shipping Temperature	-196C
Storage Temperature	-196C
Manufacturers portfolio	Cell Line (CPBU)
Manufacturers Category	Cellular Analysis
Manufacturers Product Line	Immune Checkpoint Cell Lines
Product Origin	USA

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 2 vials

Listprice: €8,500.00

Price: €8,500.00

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Delivery expected until 9/11/2025

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