Recombinant Mouse Transmembrane protease serine 6(Tmprss6),partial

Cell Biology

Tmprss6

KAEVTVSQVYSGSLRVLNRHFSQDLGRRESIAFRS ESAKAQKMLQELVASTRLGTYYNSSSVYSFGEGPL TCFFWFILDIPEYQRLTLSPEVVRELLVDELLSNS STLASYKTEYEVDPEGLVILEASVNDIVVLNSTLG CYRYSYVNPGQVLPLKGPDQQTTSCLWHLQGPEDL MIKVRLEWTRVDCRDRVAMYDAAGPLEKRLITSVY GCSRQEPVMEVLASGSVMAVVWKKGMHSYYDPFLL SVKSVAFQDCQVNLTLEGRLDTQGFLRTPYYPSYY SPSTHCSWHLTVPSLDYGLALWFDAYALRRQKYNR LCTQGQWMIQNRRLCGFRTLQPYAERIPMVASDGV TINFTSQISLTGPGVQVYYSLYNQSDPCPGEFLCS VNGLCVPACDGIKDCPNGLDERNCVCRAMFQCQED STCISLPRVCDRQPDCLNGSDEEQCQEGVPCGTFT FQCEDRSCVKKPNPECDGQSDCRDGSDEQHCDCGL QGLSSRIVGGTVSSEGEWPWQASLQIRGRHICGGA LIADRWVITAAHCFQEDSMASPKLWTVFLGKMRQN SRWPGEVSFKVSRLFLHPYHEEDSHDYDVALLQLD HPVVYSATVRPVCLPARSHFFEPGQHCWITGWGAQ REGGPVSNTLQKVDVQLVPQDLCSEAYRYQVSPRM LCAGYRKGKKDACQGDSGGPLVCREPSGRWFLAGL VSWGLGCGRPNFFGVYTRVTRVINWIQQVLT

Extracellular Domain

N-terminal 10xHis-tagged and C-terminal Myc-tagged

Matriptase-2

Membrane anchored serine proteases: a rapidly expanding group of cell surface proteolytic enzymes with potential roles in cancer.
Netzel-Arnett S., Hooper J.D., Szabo R., Madison E.L., Quigley J.P., Bugge T.H., Antalis T.M.
Cancer Metastasis Rev. 22:237-258(2003)

Liquid or Lyophilized powder

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20C/-80C. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.

Cell membrane, Single-pass type II membrane protein

Expressed at highest levels in adult mice liver, kidney and uterus. Also strongly expressed within the nasal cavity by olfactory epithelial cells. A weak, but detectable, signal in adult mice tissues analyzed including brain, lung, heart, kidney, spleen, muscle, intestine, thymus and pancreas. No signal in residual embryonic yolk sac, developing kidney tubules or in embryonic tissues analyzed including lung, heart, gastrointestinal tract and epithelium of the oral cavity.