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Recombinant Human Plasminogen activator inhibitor 2 protein(SERPINB2) (Active)

Recombinant Human Plasminogen activator inhibitor 2 protein(SERPINB2) (Active)

€1,472.00

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Item no.	CSB-AP000151HU-100
Manufacturer	Cusabio
Amount	100ug
Category	Oncology Food Safety Proteins Peptides & Proteins Recombinant Proteins By Organ Breast Cancer
Type	Proteins Recombinant
Specific against	other
Host	E.coli
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	PAI-2, Placental plasminogen activator inhibitor, Serpin B2, Urokinase inhibitor,
Available
Classification	Enzyme
Subdivision	Enzyme
Research Areas	Immunology
Uniprot NO.	P05120
Uniprot Entry Name	PAI2_HUMAN
Gene Names	SERPINB2, PAI2, PLANH2
Source	E.Coli
Expression Region	1-415aa
Sequence	MEDLCVANTL FALNLFKHLA KASPTQNLFL SP WSISSTMA MVYMGSRGST EDQMAKVLQF NEVG ANAVTP MTPENFTSCG FMQQIQKGSY PDAILQ AQAA DKIHSSFRSL SSAINASTGN YLLESVNK LF GEKSASFREE YIRLCQKYYS SEPQAVDFLE CAEEARKKIN SWVKTQTKGK IPNLLPEGSV D GDTRMVLVN AVYFKGKWKT PFEKKLNGLY PFR VNSAQRT PVQMMYLREK LNIGYIEDLK AQILE LPYAG DVSMFLLLPD EIADVSTGLE LLESEIT YDK LNKWTSKDKM AEDEVEVYIP QFKLEEHYE L RSILRSMGME DAFNKGRANF SGMSERNDLF LSEVFHQAMV DVNEEGTEAA AGTGGVMTGR TG HGGPQFVA DHPFLFLIMH KITNCILFFG RFSS
Protein Description	Full Length
Tag Info	Tag-Free
Mol. Weight	46.6 kDa
Biological Activity	Fully biologically active when compared to standard. The biologically active was determined by its inhibitory effect against single chain tPA induced cleavage of a chromogenic substrate in Imidazole Buffer at 37 C. Half maximal inhibition against 1.0 ug/ml of single chain tPA was at a concentration of 1.0 ug/ml.
Purity	>95% as determined by SDS-PAGE and HPLC.
Endotoxin	Less than 1.0 EU/ug as determined by LAL method.
Storage Buffer	0.2 um filtered 20 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1 mM Cysteine, with 5 % Trehalose , lyophilized
Alias	PAI-2, Placental plasminogen activator inhibitor, Serpin B2, Urokinase inhibitor,
Relevance	Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1.
PubMed ID	3029122; 3325828; 3496414; 3257578; 2494165; 2303256; 15489334; 1286667; 14732874; 21269460; 10368272; 10391209
Function	Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1.
Subcellular Location	Cytoplasm, Secreted, extracellular space
Protein Families	Serpin family, Ov-serpin subfamily
Paythway	Complementandcoagulationcascades

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ug

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