HDM (Der p 10) Detection Assay Kit

House dust mite (HDM) allergens are the most important indoor allergens in humans. Approximately 10% of asthma patients sensitized to HDM demonstrate IgE antibodies to the tropomyosin protein (Der p10) from dust mite, Dermatophagoides pteronyssiu. Der p10 is a 32 kDa, group 10 allergen (tropomyosins). Tropomyosins of a similar structure are found in invertebrates such as crustaceans (shrimp, lobster, crawfish, and crab), arachnids (house dust mites), insects (cockroaches), and mollusks. Tropomyosin is a heat-stable protein and sensitization may lead to severe reactions to the allergenic source. Therefore, the Der p10 antigen may play a role in the cross-induction of allergic reaction to many allergens.

Allergic Disease Models / Asthma Models

ELISA kit designed to detect and measure house dust mite (Der p10), the most common indoor allergen for human asthma, in liquid samples. The antibodies utilized in this kit are specific for mite tropomyosin protein, Der p10. from Dermatophagoides pteronyssius.