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Comparison

T47D cells

Item no. C0006001
Manufacturer Addexbio
Amount One Frozen vial
Category
Type Tumour Cells
Dry ice Yes
Citations 1.Afhuppe, W., Sommer, A., Muller, J., Schwede, W., Fuhrmann, U., and Moller, C. Global gene expression profiling of progesterone receptor modulators in T47D cells provides a new classification system. J Steroid Biochem Mol Biol, 113: 105-115, 2009.
2.Chen, Y., Huang, K., Chen, K. E., and Walker, A. M. Prolactin and estradiol utilize distinct mechanisms to increase serine-118 phosphorylation and decrease levels of estrogen receptor alpha in T47D breast cancer cells. Breast Cancer Res Treat, 120: 369-377.
3.Holley, A. K., Kiningham, K. K., Spitz, D. R., Edwards, D. P., Jenkins, J. T., and Moore, M. R. Progestin stimulation of manganese superoxide dismutase and invasive properties in T47D human breast cancer cells. J Steroid Biochem Mol Biol, 117: 23-30, 2009.
4.Hua, D., Chen, B., Bai, M., Yu, H., Wu, X., and Jin, W. PEA3 activates VEGF transcription in T47D and SKBR3 breast cancer cells. Acta Biochim Biophys Sin (Shanghai), 41: 63-68, 2009.
5.Sanada, N., Gotoh, Y., Shimazawa, R., Klinge, C. M., and Kizu, R. Repression of activated aryl hydrocarbon receptor-induced transcriptional activation by 5alpha-dihydrotestosterone in human prostate cancer LNCaP and human breast cancer T47D cells. J Pharmacol Sci, 109: 380-387, 2009.
6.Zhang, Y., Zhao, H., Asztalos, S., Chisamore, M., Sitabkhan, Y., and Tonetti, D. A. Estradiol-induced regression in T47D:A18/PKCalpha tumors requires the estrogen receptor and interaction with the extracellular matrix. Mol Cancer Res, 7: 498-510, 2009.
ECLASS 10.1 32160890
ECLASS 11.0 32160890
UNSPSC 41106509
Available
Description

Disease:

Breast ductal carcinoma

Origin:

Derived from metastatic pleural effusion

Species:

Homo sapiens

Tissue:

Breast

Morphology:

Epithelial

Properties:

Adherent

Cytogenic data:

This is a hypotriploid human cell line

Patient:

Female, 54 yrs of age

Medium:

AddexBio-formulated RPMI-1640 Medium(C0004-01) + 10% FBS

Subculture:

1:3 to 1:5 using 0.25% trypsin or trypsin/EDTA, 5% CO2; 37C

Freezing Medium:

Complete culture medium supplemented with 5% (v/v) DMSO

Biosafety Level:

I

Sterility:

Bacteria: Negative

Yeast: Negative

Mycoplasma: Negative

Pathogens:

HIV: Negative

Hepatitis B: Negative

Hepatitis C: Negative

Protein Expression:

calcitonin, androgen receptor, estrogen receptor, progesterone receptor, glucocorticoid receptor, prolactin,

Isoenzymes:

AK-1, 1; ES-D, 2; G6PD, B; GLO-I, 1-2; PGM1, 1; PGM3, 1

DNA Profile (STR):

Amelogenin: X

CSF1PO: 11, 13

D13S317: 12

D16S539: 10

D5S818: 12

D7S820: 11

THO1: 6

TPOX: 11

vWA: 14

Citation Format:

If use of this culture results in a scientific publication, it should be cited in the publication as: T47D (AddexBio C0006001)

Mutations in T47D Cells

Related cells by Organ:

4T1

AU-565

BT-20

BT-474

BT-483

BT-549

JIMT-1

MCF-7

SK-BR-3

T47D

ZR-75-1

Storage condition
LN2
Manufacturers Category
Cell Lines

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: One Frozen vial
Available: In stock
available

Delivery expected until 7/31/2025 

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