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OxiSelect™ Oxidative DNA Damage Quantitation Kit (AP sites)

OxiSelect™ Oxidative DNA Damage Quantitation Kit (AP sites)

€843.00

Excl. VAT

Item no.	STA-324
Manufacturer	Cell Biolabs
Amount	50 assays
Category	Cell Biology Cell Status Oxidative Stress Other Assays & Kits Other Kits
Type	Kit
Specific against	other
ECLASS 10.1	32161090
ECLASS 11.0	32161090
UNSPSC	41116126
Available
Description	DNA damage can manifest In the formation of apurinic or apyrimidinic (AP or abasic) sites. Such spontaneous base loss In mammalian cells has been estimated at between 50, 000 and 200, 000 sites per day. Unrepaired abasic sites can Inhibit transcription and may be mutagenic. Our OxiSelect Oxidative DNA Damage Quantitation Kit provides a simple, user-friendly method for the quantitaiton DNA damage In the form of abasic sites. The assay uses an Aldehyde Reactive Probe (ARP) to specifically react with an aldehyde group on the open ring of the AP site. This allows the AP site to be labeled with Biotin, followed by detection with Streptavidin-Enzyme conjugate.
Formulation	1. Detect as few as 4-40 AP sites In 10^5 bp DNA 2. Suitable for use with cells or tissues 3. Oxidized and reduced DNA standards Included for absolute quantitation
Shipping Temp	Room Temp
Storage Temp	Upon receipt, aliquot and store both the Reduced DNA and ARP-DNA Standards at -20C to avoid multiple freeze/thaw cycles. Store all other components at 4C.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.