Ac-Cys-OH

NAC induced apoptosis in rat and human smooth muscle cells and serves as an efficient substrate for the rat liver microsomal glutathione transferase with 1-chloro-2, 4-dinitrobenzene as second substrate. The conjugate with phenethyl isothiocyanate induces apoptosis predominantly in growth-promoted cells, which leads to the assumption that this conjugate inhibits lung carcinogenesis. Furthermore, NAC has been found to act as a specific inhibitor of TGF-beta signaling targeting different components of the TGF-beta signaling machinery. Bachem also offers the dimer of NAC, DiNAC (E-2965).