Anti-SNRNP200 antibody

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

O75643

Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.

SNRNP200

Rabbit polyclonal against SNRNP200

Nucleus

WB 1:500-1:2000

U5 Small Nuclear Ribonucleoprotein 200 Kda Helicase
Activating Signal Cointegrator 1 Complex Subunit 3-Like 1
Brr2 Homolog
U5 Snrnp-Specific 200 Kda Protein
U5-200kd

U520_HUMAN