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Bizelesin

Bizelesin

€48,900.00

Excl. VAT

Item no.	TRC-B591700-100mg
Manufacturer	Toronto Research Chemicals
Amount	100mg
Category	Reagents & Chemicals Other Chemicals
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
CAS Number	129655-21-6
Mol. Formula	C43H36Cl2N8O5
Mol. Weight	815, 7
Subcategory	Chiral Reagents, Indole Derivatives, Pharmaceuticals, Intermediates & Fine Chemicals
Appearance	No Data Available
Application Notes	As members of the cyclopropylpyrroloindole family, Adozelesin and Bizelesin cause genomic DNA lesions by alkylating DNA. Adozelesin induces single-strand DNA lesions, whereas Bizelesin induces both single-strand lesions and double-strand DNA cross-links. Thus, despite similar abilities to alkylate DNA, the chemotherapeutic agents Adozelesin and Bizelesin caused a decrease in HCT116 tumor cell proliferation by different pathways (i.e., Adozelesin induced apoptosis, and Bizelesin induced senescence).
Melting Pt.	No Data Available
Boiling Pt.	No Data Available
Solubility	No Data Available
Stability	No Data Available
Storage Condition	No Data Available

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100mg

Listprice: €48,900.00

Price: €48,900.00

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Delivery expected until 9/4/2025

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