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BDNF Protein, Mouse (R129A, R130A, HEK293, His)

BDNF Protein, Mouse (R129A, R130A, HEK293, His)

€221.00

Excl. VAT

Item no.	HY-P74383-10ug
Manufacturer	MedChem Express
Amount	10 ug
Category	Inhibitors & Compound Libraries Small Molecules
Type	Peptides
Specific against	other
Purity	98.0
Dry ice	Yes
Citations	[1]Bathina S, et al. Brain-derived neurotrophic factor and its clinical implications. Arch Med Sci. 2015 Dec 10;11(6):1164-78. [2]Lima Giacobbo B, et al. Brain-Derived Neurotrophic Factor in Brain Disorders: Focus on Neuroinflammation. Mol Neurobiol. 2019 May;56(5):3295-3312. [3]Patterson SL, et al. Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice. Neuron. 1996 Jun;16(6):1137-45.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	BDNF Protein, Mouse (R129A, R130A, HEK293, His, Solution),Mouse,HEK293
Available
Product Description	Brain Derived Neurotrophic Factor (BDNF) is a neurotrophin that belongs to NGF-beta family. BDNF can bind to its high affinity receptor TrkB and activates signal transduction cascades (IRS1/2, PI3K, Akt)[1]. BDNF can also bind to the p75NTR, but the affinity for the p75NTR receptor is lower than for TrkB[2]. BDNF is a neurotransmitter modulator, and is vital in maturation, survival and differentiation of neuronal populations during development. BDNF also participates in neuronal plasticity, which is essential for learning and memory. BDNF is widely expressed in the CNS[1]. BDNF Protein, Mouse (R129A, R130A, HEK293, His) is a recombinant mouse BDNF (M1-R249, R129A, R130A) with C-terminal His tag, which is produced in HEK293.
StorageTemperature	Stored at -80°C for 1 year
Shipping	Dry Ice
Molecular Weight	Approximately 27.4 kDa
Manufacturers Product type	Recombinant Proteins

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

Listprice: €221.00

Price: €221.00

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