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RNF2 Antibody, KO Validated

RNF2 Antibody, KO Validated

€522.00

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Item no.	PRS-18-266-50uL
Manufacturer	ProSci
Amount	50 uL
Category	Oncology Neuroscience Molecular Targets for Neuroscience Antibodies By Cell Type Carcinoma Hematology Lymphoma Myeloma Melanoma Sarcoma Mesothelioma Immunohistochemistry Immunoprecipitation Western Blot Immunofluorescence Primary Antibodies CHiP
Type	Antibody Primary
Format	Liquid
Applications	WB, IF, IP, IHC, CHIP
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	RNF2, BAP1, DING, BAP-1, HIPI3, RING2, RING1B
Available
Shipping	blue ice or RT
By Research Area	Other
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-336 of human RNF2 (NP_009143.1).
Applications	WB: 1:500 - 1:2000 IHC: 1:50 - 1:200 IF: 1:50 - 1:200 IP: 1:50 - 1:200 ChIP: 1:50 - 1:200
Positive Control 1	HeLa
Predicted Molecular Weight	Observed: 38kDa
Validation	Antibody is Knockout validated.
Purification	Affinity purification
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	RNF2
Ncbi Gene Id #	6045
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	RNF2
Ncbi Official Full Name	ring finger protein 2
Ncbi Organism	Homo sapiens
Swissprot #	Q99496
Background	Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.
1st Image Caption	Western blot analysis of extracts from normal (control) and RNF2 knockout (KO) HeLa cells, using RNF2 antibody (18-266) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 uL

Listprice: €522.00

Price: €522.00

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Delivery expected until 9/4/2025

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